产品货号：
Z17736
中文名称：
HDAC7 (N-terminus)抗体
英文名称：
Anti-HDAC7 (N-terminus) Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HDAC7 (N-terminus) Antibody |
| 指标别名 | HD7;HD7A;HDAC7;HDAC7A;histone deacetylase 7;Histone deacetylase 7A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,primate,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | HDAC7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | HDAC7 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N terminal region of human HDAC7. |
| 计算分子量 | 103kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | Anti-HDAC7 was affinity purified from monospecific antiserum by immunoaffinity chromatography.This antibody is specific towards HDAC7.A BLAST analysis was used to suggest cross-reactivity with Human,Mouse,Rat and Primate based on 100% sequence homology.Cross-reactivity with HDAC7 from other sources has not been determined. |
| 浓度 | 1.16mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is six (6) months from date of opening. |
| 背景资料 | HDAC7 is a member of the class II mammalian histone deacetylases,which plays an important role in modulating the eukaryotic chromatin structure.Human HDAC7 is composed of 912 amino acid residues.Although HDAC7 is localized mostly to the cell nucleus,it is also found in the cytoplasm,suggesting nucleo-cytoplasmic shuttling.The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus.It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors.HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions,leading to the inhibition of gene transcription.Anti-HDAC7 antibodies are ideal for researches interested in Breast Cancer,Cancer,Cell Cycle and Replication,Chromatin Research,Epigenetics,and Histone Deacetylases research. |
| Uniprot ID | Q8WUI4 |
| 基因名全称 | Histone deacetylase 7 |
| 推荐稀释比 | ELISA:1:20,000 - 1:60,000 IHC:1:100～1:500 IF Microscopy:1:100～1:500 WB:1μg/mL |
相关搜索：HDAC7 (N-terminus)抗体，HDAC7 (N-terminus)多抗，Anti-HDAC7 (N-terminus) Antibody