加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

HDAC7 (N-terminus)抗体图片
产品货号:
Z17736
中文名称:
HDAC7 (N-terminus)抗体
英文名称:
Anti-HDAC7 (N-terminus) Antibody
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-HDAC7 (N-terminus) Antibody
指标别名HD7;HD7A;HDAC7;HDAC7A;histone deacetylase 7;Histone deacetylase 7A
克隆性Polyclonal
检验物种human,mouse,primate,rat
应用范围ELISA,WB
基因名称HDAC7
抗体来源Rabbit
抗体类型IgG
免疫原HDAC7 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N terminal region of human HDAC7.
计算分子量103kDa
成分0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide
纯化方式Anti-HDAC7 was affinity purified from monospecific antiserum by immunoaffinity chromatography.This antibody is specific towards HDAC7.A BLAST analysis was used to suggest cross-reactivity with Human,Mouse,Rat and Primate based on 100% sequence homology.Cross-reactivity with HDAC7 from other sources has not been determined.
浓度1.16mg/mL by UV absorbance at 280nm
产品形态溶液
保存条件Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is six (6) months from date of opening.
背景资料HDAC7 is a member of the class II mammalian histone deacetylases,which plays an important role in modulating the eukaryotic chromatin structure.Human HDAC7 is composed of 912 amino acid residues.Although HDAC7 is localized mostly to the cell nucleus,it is also found in the cytoplasm,suggesting nucleo-cytoplasmic shuttling.The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus.It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors.HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions,leading to the inhibition of gene transcription.Anti-HDAC7 antibodies are ideal for researches interested in Breast Cancer,Cancer,Cell Cycle and Replication,Chromatin Research,Epigenetics,and Histone Deacetylases research.
Uniprot IDQ8WUI4
基因名全称Histone deacetylase 7
推荐稀释比ELISA:1:20,000 - 1:60,000
IHC:1:100~1:500
IF Microscopy:1:100~1:500
WB:1μg/mL

相关搜索:HDAC7 (N-terminus)抗体HDAC7 (N-terminus)多抗Anti-HDAC7 (N-terminus) Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3